ketotifen

[preistfan]

I found this post on promusclemag.com about ketotifen. I have used keto before and it definitely helped me so I wanted to pass some info on those of you who may not be familiar with it. I'm using it for the appetite increase and to upregulate by receptors for the next time I use clen, eph, etc.

Ketotifen - what you need to know by CYCLEON

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I see a lot of newbie people trying to find good info on this so I thought it would be best to put it all in one place. I patched this from a wide range of sources as well as my own experience (also thanks to FONZ). This truly is a wonderdrug for BB.

What Is It?
Ketotifen is very safe antihistamine used extensively in Europe to treat bronchial asthma and allergies. It is also being studied as a treatment for colitis. When used for asthma, weight gain and an increase in appetite are among the most frequent side effects. Ketotifen also protects the cells in the stomach, small intestine and perhaps the rest of the gut from a number of toxins. A number of case studies suggest that it may be helpful treating skin problems such as acne. Ketotifen also reduces edema (swelling and puffiness caused by water retention) around sores.

Ketotifen Studies
German researchers have published data showing that ketotifen lowers tnf-alpha in the test tube. One study used ketotifen in combination with oxymethadone, a steroid like Megace that helps people gain weight, so it is hard to gauge what effect ketotifen had (the study notes a 14% reduction in TNF-alpha levels and weight gains of 11-12 pounds in less than four weeks). A larger placebo controlled study of this combination is underway. The other study used ketotifen by itself in eight patients with elevated TNF-alpha, (but no wasting). Taking ketotifen for 12 weeks, these patients gained an average of six pounds, had increases in their body cell mass and reductions in their TNF-alpha levels.

Side Effects and Toxicity
Ketotifen is virtually non-toxic (although it is not advised for patients with epilepsy). People who took twenty times the recommended dose (in suicide attempts) suffered no serious consequences (other than embarrassment). Its primary side effects seem to be temporary drowsiness, dry mouth,(and other mucuos membranes) appetite stimulation and weight gain.

Dosing and side effects
No studies have been done to find the most effective dose but the German researchers used 4 mg ED. Dan Duchaine (who discovered ketos use for BB) suggested 10mg ED but in my experience this much is not needed and makes u far too sleepy. I find that 3-4mg ED seems ideal. However, much higher doses have been shown to be quite safe with no adverse affects other than increased drowsiness and appetite – it will make u hungry for solid foods. You can take it divided in the day or all at once but I find I get waay too sleepy if its all at once - not to mention my clen feels like its going to make my heart jump out of my chest, so divided doses is the best IMO.

Ketotifen and Clen Clenbuterol is a beta 2 agonist which has a limited anabolic effect during its first few days of use and afterward is normally used to fight fat. At higher doses, however, it can be catabolic to muscle and it must be cycled on a 2 week on, 2 week of basis or the beta 2 receptors that Clen binds to become saturated and down regulate.

Ketotifen’s magic is that it upregulates the beta-receptors including the beta 2s that Clen uses. As long as you are taking ketotifen, it will continue to clean these receptors, never allowing them to downregulate – even while on a heavy Clen cycle. That means you can continue to take Clen indefinitely without having to cycle off to regenerate the receptors. 2-3mg ED can upregulate even severely shut down receptors within a week.

It also means that you don’t need as much Clen to get the same benefits. It seems u can take about 30-40% less Clen and it be equally effective. FONZ posted that it also increases the number of receptor sites on the surface of the cell, allowing more Clen to attach and perhaps this is the reason for the increased efficacy. Ketotifen also seems to lessen the sides of Clen including the jitters but it can make you drowsy as hell if you take too much at one time. A second benefit is you can use it to knock you out if you cant sleep.

Ketotifen and ECA
Perhaps an even better use for ketotifen is taking it with the ECA stack. While the thermogenic effect of ephedrine is not as potent as Clen because it doesn't have a high receptor affinity, and it is not limited to beta-2 receptors. In fact it seems to have a good effect on beta 3 receptors as well, which act as a type of thermogenic messenger and over half of ephedrine effect is from beta-3 stimulation. Clen has almost no effect on beta 3 however. So by keeping the beta 2 receptors up, ketotifen can allow the benefits of continuous beta 2 and beta 3 stimulation from ephedrine.

[demonsweat]

Thanks for the info Priestfan! I was just looking into Ketotifen last night and thinking I need to gather more info on it. Seems like a very interesting compound especially when used in conjunction with Clen.

[aliceinchains]

Is it true that dyphenhydramine is almost as good as 'tifen ay keeping beta 2's up?

[MuscleHustle]

great read!thanks for the post

[seventhlttd]

very good read..

[lostinfitness]

Very good post bro, I have seen good results with keto/clen blend last year.

[jdjack]

Bravo jackass keep waking the dead.