Lipids jacked

[AMlabs]

My cholesterol is all jacked up after using some super drol. Never had any issues in the last 9 years of use and have been on about a year now. Had it checked earlier this year 119 total 60/40 ration good to bad. Checked the last day of SD cycle 192 total hdl 10 ldl 182. All I can say is holy fuck.
What are some good tricks to lower it faster? I know i'll go back to low 100 but want it done fast. Var did the same thing to me 5 years ago.
Any advice other than fiber, garlic and nolvadex.

[Kosher Fried]

statins

red yeast rice

flush free niacin

.you're better than me...TBOL sent my totals to 267..HDL of FIVE!

[AMlabs]

Statins?

[balookis]

I'm curious...what is the draw to using something like Super Drol when you are already using real gear? Isn't Super Drol just a lesser version of the real thing with reduced gains and more sides?

Not trying to be a dick...I'm really curious.

[AMlabs]

Originally Posted by balookis

I'm curious...what is the draw to using something like Super Drol when you are already using real gear? Isn't Super Drol just a lesser version of the real thing with reduced gains and more sides?

Not trying to be a dick...I'm really curious.

Thought i was going to have to take a drug test. SD is legal and 300mg of test is undetectable so thats what i did. Ill never take it again. Acne, bloat and this, no thanks.
Am

[Magni]

A statin like Lipitor or Crestor.

You may want to take a look at GHRP, Dlys3 GHRP or Hexarelin. Many research companies carry this.

" Growth hormone releasing peptides (GHRPs), a family of synthetic analogs modelled from Met-enkephalin, have been found to bind a novel class of specific GHRP receptors in the mammalian heart that are distinct from the pituitary GHRP receptors involved in GH secretion. CD36, a multifunctional B-type scavenger receptor, has been identified as the unique GHRP binding site in the heart. CD36 mediates the uptake of lipoproteins into a number of cell types and was recognized to play a crucial role in scavenging oxidized low density lipoproteins in monocyte/ macrophages leading to foam cell formation, a key step in fatty streaks formation.
The hexapeptide GHRP prototypes hexarelin (His - DMe - Trp - Ala - Trp - D Phe - Lys - NH2) and EP 80317 (Haic-D Me - Trp -D Lys - Trp - D Phe- Lys NH2), the latter analog being devoid of GH-secreting activity in vivo, have been shown to reduce fatty streak lesions and hypercholesterolemia in apolipoprotein E (Apo E) null mice fed a high fat high cholesterol diet (HFHC). In addition, non-HDL cholesterol was significantly decreased, whereas HDL cholesterol tended to increase. GHRP treatment also inhibited oxLDL-induced monocyte chemotaxis in the peritoneal cavity, which was associated with a reduced expression of the CD36 protein on peritoneal monocytes/macrophages.
GHRPs may represent a novel therapeutic avenue to reduce the severe morbidity associated with the arterial disease atherosclerosis and its complications, such as myocardial infarction and strokes, that occur despite current management strategies."

[balookis]

Originally Posted by AMlabs

Thought i was going to have to take a drug test. SD is legal and 300mg of test is undetectable so thats what i did. Ill never take it again. Acne, bloat and this, no thanks.
Am

Ahh...gotcha. Glad I never messed with that stuff. I thought about it.

[onemuscledbeagle]

Originally Posted by Kosher Fried

statins

red yeast rice

flush free niacin

.you're better than me...TBOL sent my totals to 267..HDL of FIVE!

I concur with Kosher with these OTC options. Just make sure you pick up the slow release niacin otherwise you are going to flush like a cherry. From my personal/professional experience, statins would be my first choice to get the greatest reduction the fastest on total CHL and LDL's. However, the HDL's are slower to respond. Make sure you are putting time in on CV training as well for the HDL's.

[Lockk]

Originally Posted by AMlabs

Statins?

A little bit of info for ya on Satins AM.

Statins are a class of drugs used to treat high lipids, especially high LDL cholesterol. They include simvastatin (Zocor), pravastatin (Lipostat), fluvastatin (Lescol / Lescol XL), atorvastatin (Lipitor), cerivastatin and rosuvastatin (Crestor). The statins are more effective than other classes of lipid-lowering drugs at reducing LDL cholesterol, but less effective than the fibrates in reducing triglycerides and increasing HDL cholesterol. In the general population, they reduce the risk of heart disease, stroke, diabetes and death.

Statins are generally regarded as very safe drugs, although their main side-effects are gastrointestinal problems (nausea, vomiting, flatulence and stomach pain) and inflammation of the muscles. A person taking a statin is advised to report muscle weakness, tenderness or pain to their doctor promptly. The risk of muscle pain and weakness is increased if a statin is taken with gemfibrozil (Lopid), ciclosporin (Neoral / Sandimmun) or nicotinic acid. Kidney and liver function should be closely monitored if these drugs are taken with a statin.

Most statins are metabolised in the liver in a similar way to the protease inhibitors, primarily using the P450 CYP3A4 pathway. Some protease inhibitors cause substantial and potentially dangerous increases in blood levels of statins, increasing the risk of muscle damage. Drug interaction studies in HIV-negative subjects found large increases in atorvastatin and simvastatin levels when dosed with saquinavir (Invirase / Fortovase) and ritonavir (Norvir). However, the decline in pravastatin levels was less pronounced, indicating this may be the safest statin for use with protease inhibitors. Another study has recommended that simvastatin not be taken with nelfinavir (Viracept) due to a drug interaction, and that caution should be exercised when nelfinavir and atorvastatin are co-administered. Similarly, efavirenz (Sustiva) can cause reduced exposure to simvastatin, pravastatin and atorvastatin, possibly requiring higher doses to maintin the drugs' lipid-lowering actions (Gerber 2005).

In contrast to other members of the drug class, rosuvastatin is not metabolised by the P450 pathway. A pilot study has shown that it is a safe and effective treatment for increased cholesterol and triglycerides in patients taking protease inhibitors (Calza 2005).

Other drugs can also interact with the statins. For example, when fluvastatin is taken concurrently with fluconazole (Diflucan), levels of fluvastatin are elevated and exposure is prolonged.

A recent study has suggested that statins may also have a direct antiretroviral activity, through their inhibition of the enzyme Rho guanosine triphosphatase. This prevents the formation of the protein Rho, which is necessary for the entry of HIV into T-cells and the release of virus particles from infected cells. In their small proof-of-concept study, the investigators showed that giving lovastatin to antiretroviral-naive patients for one month caused reductions in viral load and increases in CD4 cell counts (del Real 2004). However, this finding requires verification in further clinical studies.

Similarly, some doctors have expressed concern that statins may affect the levels of immune system cells and chemical messengers or 'cytokines', potentially altering the course of HIV disease or therapy. Despite their beneficial effects on lipid levels, they warn that more research is needed to establish whether the drugs have long-term effects on the immune system (Corrales-Medina 2005).

[Lockk]

A little info on Niacin.


Nicotinic acid or niacin
Nicotinic acid is also known as vitamin B3 or niacin. In the human body niacin plays a role in fat synthesis, protein and carbohydrate breakdown, tissue respiration and digestion.

As a high dose supplement, niacin is effective at lowering both cholesterol and triglycerides in people taking antiretroviral therapy but its use is limited due to side-effects including dilation of the veins, headache, flushing, dizziness, palpitations, nausea, and insulin resistance (Gerber 2003). A second member of this group, acipimox (Olbetam), has fewer side-effects but is less effective at reducing lipids.