[Ronn]

Isotrentinion is the active ingredient in accutane.

I've used it at both 10mgs daily and 20mgs--it works.

My decision to used accutane is probably different than most. I don't have a lot of acne, it's just that in my mid-forties, I don't feel I should have any--I haven't been a teenager for a quarter of a century and there's a time some things simply need to be done with. I've gotten about one zit a day or so ever since the sever acne I had as an adolescent cleared up (in my early 20's). And having a fair completion, a bad zit will scar me for over a year. I started using Isotrentinion at 10mgs per day and found it to be fairly effective, cutting me down to about one or two new zits a week—none of which advanced to cystic state (hence no scarring acne since about 20 days after I started using it). So, listening to ORBIS’s cautionary tale, you might start at that dosage. And mine acne never got worse, it merely remained unaffected until about 20 days in. However, as I stated my pathology is different that those commonly encountered when this drug is being considered.

If you're using HRT supplementation of any kind, I might consider moving to 20mgs at least.

The side effects I noticed include dry skin and lips (which my body compensated for after about a month), a flushed complexion (which never compensated) and I’m sure elevated liver enzymes (though I have no blood work to confirm that).

ORBIS's response seems extreme, however when self administering drugs, prudence is always a useful policy.

Hope that helps,

Ronn